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1

Selenium and Selenoproteins in Health and Disease

Papp, Laura V., Holmgren, Arne, Khanna, Kum Kum

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

2

Targeting homologous recombination, new pre-clinical and clinical therapeutic combinations inhibiting RAD51

Ward, Ambber, Khanna, Kum Kum, Wiegmans, Adrian P.

Journal:

Cancer Treatment Reviews

Year:

2015

Language:

english

File:

PDF, 1.32 MB

english, 2015

3

Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease

Kalimutho, Murugan, Parsons, Kate, Mittal, Deepak, López, J. Alejandro, Srihari, Sriganesh, Khanna, Kum Kum

Journal:

Trends in Pharmacological Sciences

Year:

2015

Language:

english

File:

PDF, 5.07 MB

english, 2015

4

A Comprehensive Review on Current Advances in Peptide Drug Development and Design

Lee, Andy Chi-Lung, Harris, Janelle Louise, Khanna, Kum Kum, Hong, Ji-Hong

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.27 MB

english, 2019

5

Chromosome arm aneuploidies shape tumour evolution and drug response

Shukla, Ankit, Nguyen, Thu H. M., Moka, Sarat B., Ellis, Jonathan J., Grady, John P., Oey, Harald, Cristino, Alexandre S., Khanna, Kum Kum, Kroese, Dirk P., Krause, Lutz, Dray, Eloise, Fink, J. Lynn,

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 1.85 MB

english, 2020

6

The implication of the SUMOylation pathway in breast cancer pathogenesis and treatment

Rabellino, Andrea, Khanna, Kum Kum

Journal:

Critical Reviews in Biochemistry and Molecular Biology

Year:

2020

Language:

english

File:

PDF, 1.79 MB

english, 2020

7

p73 Is up-regulated in a subset of hepatocellular carcinomas

Nirmitha I. Herath, Michael C. Kew, Vicki L. Whitehall, Michael D. Walsh, Jeremy R. Jass, Kum Kum Khanna, Joanne Young, Lawrie W. Powell, Barbara A. Leggett, Dr. Graeme A. Macdonald

Journal:

Year:

2000

Language:

english

File:

PDF, 204 KB

english, 2000

8

Beta-amyloid increases the expression level of ATBF1 responsible for death in cultured cortical neurons

Cha-Gyun Jung, Kyung-Ok Uhm, Yutaka Miura, Takashi Hosono, Hirofumi Horike, Kum Kum Khanna, Mi-Jeong Kim, Makoto Michikawa

Journal:

Molecular Neurodegeneration

Year:

2011

Language:

english

File:

PDF, 2.78 MB

english, 2011

9

ATM mediated phosphorylation of CHD4 contributes to genome maintenance

Aaron J Urquhart, Magtouf Gatei, Derek J Richard, Kum Kum Khanna

Journal:

Genome Integrity

Year:

2011

Language:

english

File:

PDF, 4.21 MB

english, 2011

10

An ultrastructural analysis of changes in surface architecture of intestinal mucosa followingGiardia lambliainfection in mice

R. Khanna, K. Joshi, Kum Kum, A. K. Malik, V. K. Vinayak

Journal:

Journal of Gastroenterology

Year:

1990

Language:

english

File:

PDF, 3.97 MB

english, 1990

11

ATM protein kinase: the linchpin of cellular defenses to stress

Shahzad Bhatti, Sergei Kozlov, Ammad Ahmad Farooqi, Ali Naqi, Martin Lavin, Kum Kum Khanna

Journal:

Cellular and Molecular Life Sciences

Year:

2011

Language:

english

File:

PDF, 859 KB

english, 2011

12

Mutation analysis of five candidate genes in familial breast cancer

Anna Marsh, Sue Healey, Aaron Lewis, Amanda B. Spurdle, Mary Anne Kedda, Kum Kum Khanna, kConFab, Graham J. Mann, Gulietta M. Pupo, Sunil R. Lakhani, Georgia Chenevix-Trench

Journal:

Breast Cancer Research and Treatment

Year:

2007

Language:

english

File:

PDF, 187 KB

english, 2007

13

Mutation analysis ofRAD51L1(RAD51B/REC2) in multiple-case, non-BRCA1/2breast cancer families

Julie Johnson, Sue Healey, Kum Kum Khanna, kConFab, Georgia Chenevix-Trench

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 451 KB

english, 2011

14

Gut-associated immune effector responses in immunocompetent and immunocomprimised mice with Giardia lamblia

R. Khanna, Kum Kum, V.K. Vinayak

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 594 KB

english, 1990

15

Interaction between ATM protein and c-Abl in response to DNA damage

Shafman, Timothy, Khanna, Kum Kum, Kedar, Padmini, Spring, Kevin, Kozlov, Sergei, Yen, Tim, Hobson, Karen, Gatei, Magtouf, Zhang, Ning, Watters, Dianne

Journal:

Year:

1997

File:

PDF, 1.40 MB

1997

16

10.1038/3882

Khanna, Kum Kum, Keating, Katherine E., Kozlov, Sergei, Scott, Shaun, Gatei, Magtouf, Hobson, Karen, Taya, Yoichi, Gabrielli, Brian, Chan, Doug, Lees-Miller, Susan P., Lavin, Martin F.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

17

10.1038/85798

Khanna, Kum Kum, Jackson, Stephen P.

Journal:

Nature Genetics

Year:

2001

Language:

english

File:

PDF, 255 KB

english, 2001

18

Sequential changes of lamina propria immunoglobulin-containing cells in immune intact and immunosuppressed mice infected with Giardia lamblia

Vinayak, VK, Khanna, R, Kum, Kum

Journal:

Immunology & Cell Biology

Year:

1989

Language:

english

File:

PDF, 1.88 MB

english, 1989

19

Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A

Goodarzi, Aaron A, Jonnalagadda, Jyoti C, Douglas, Pauline, Young, David, Ye, Ruiqiong, Moorhead, Greg B G, Lees-Miller, Susan P, Khanna, Kum Kum

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 506 KB

english, 2004

20

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

Watters, Dianne, Khanna, Kum Kum, Beamish, Heather, Birrell, Geoffrey, Spring, Kevin, Kedar, Padmini, Gatei, Magtouf, Stenzel, Deborah, Hobson, Karen, Kozlov, Sergei

Journal:

Year:

1997

Language:

english

File:

PDF, 1.27 MB

english, 1997

21

An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells

Zhang, Ning, Chen, Phil, Gatei, Magtouf, Scott, Shaun, Khanna, Kum Kum, Lavin, Martin F

Journal:

Year:

1998

Language:

english

File:

PDF, 349 KB

english, 1998

22

Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells

Chen, Philip, Gatei, Magtouf, O'Connell, Matthew J, Khanna, Kum Kum, Bugg, Sarah J, Hogg, Annette, Scott, Shaun P, Hobson, Karen, Lavin, Martin F

Journal:

Year:

1999

Language:

english

File:

PDF, 368 KB

english, 1999

23

Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by α-lipoic acid

Gatei, Magtouf, Shkedy, Dganit, Khanna, Kum Kum, Uziel, Tamar, Shiloh, Yosef, Pandita, Tej K, Lavin, Martin F, Rotman, Galit

Journal:

Year:

2001

Language:

english

File:

PDF, 181 KB

english, 2001

24

Expression of a Truncated Brca1 Protein Delays Lactational Mammary Development in Transgenic Mice

Melissa A. Brown, Hans Nicolai, Kathy Howe, Toyomasa Katagiri, El-Nasir Lalani, Kaylene J. Simpson, Nathan W. Manning, Andrew Deans, Phil Chen, Kum Kum Khanna, Mas Rina Wati, Beatrice L. Griffiths, Ch

Journal:

Transgenic Research

Year:

2002

Language:

english

File:

PDF, 428 KB

english, 2002

25

ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility

Kum Kum Khanna, Georgia Chenevix-Trench

Journal:

Journal of Mammary Gland Biology and Neoplasia

Year:

2004

Language:

english

File:

PDF, 366 KB

english, 2004

26

Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions

Nozomi Tomimatsu, Bipasha Mukherjee, Katherine Deland, Akihiro Kurimasa, Emma Bolderson, Kum Kum Khanna, Sandeep Burma

Journal:

Year:

2012

Language:

english

File:

PDF, 883 KB

english, 2012

27

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A

Claus Storgaard Sørensen, Randi G. Syljuåsen, Jacob Falck, Tine Schroeder, Lars Rönnstrand, Kum Kum Khanna, Bin-Bing Zhou, Jiri Bartek, Jiri Lukas

Journal:

Year:

2003

Language:

english

File:

PDF, 392 KB

english, 2003

28

Cloning and Expression of the Ataxia–Telangiectasia Gene in Baculovirus

Shaun P. Scott, Ning Zhang, Kum Kum Khanna, Alexander Khromykh, Karen Hobson, Dianne Watters, Martin F. Lavin

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

29

Functional Characterization of Cultured Cells Derived from an Intraepidermal Carcinoma of the Skin (IEC-1)

Anthony J. Dicker, Magdalena M. Serewko, Alison L. Dahler, Kum Kum Khanna, Pritinder Kaur, Amy Li, Geoff M. Strutton, Nicholas A. Saunders

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 304 KB

english, 2000

30

Cdk1/Erk2- and Plk1-Dependent Phosphorylation of a Centrosome Protein, Cep55, Is Required for Its Recruitment to Midbody and Cytokinesis

Megan Fabbro, Bin-Bing Zhou, Mikiko Takahashi, Boris Sarcevic, Preeti Lal, Mark E. Graham, Brian G. Gabrielli, Phillip J. Robinson, Erich A. Nigg, Yoshitaka Ono, Kum Kum Khanna

Journal:

Developmental Cell

Year:

2005

Language:

english

File:

PDF, 873 KB

english, 2005

31

Application of molecular findings to the diagnosis and management of breast disease: recent advances and challenges

Peter T. Simpson, Ana-Cristina Vargas, Fares Al-Ejeh, Kum Kum Khanna, Georgia Chenevix-Trench, Sunil R. Lakhani

Journal:

Human Pathology

Year:

2011

Language:

english

File:

PDF, 990 KB

english, 2011

32

A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation

Michael Hinz, Michael Stilmann, Seda Çöl Arslan, Kum Kum Khanna, Gunnar Dittmar, Claus Scheidereit

Journal:

Year:

2010

Language:

english

File:

PDF, 1.57 MB

english, 2010

33

Skp2 E3 Ligase Integrates ATM Activation and Homologous Recombination Repair by Ubiquitinating NBS1

Juan Wu, Xian Zhang, Ling Zhang, Ching-Yuan Wu, Abdol Hossein Rezaeian, Chia-Hsin Chan, Ju-Mei Li, Jing Wang, Yuan Gao, Fei Han, Yun Seong Jeong, Xiandao Yuan, Kum Kum Khanna, Jianping Jin, Yi-Xin Zen

Journal:

Year:

2012

Language:

english

File:

PDF, 1.36 MB

english, 2012

34

The DNA Damage Response: Implications on Cancer Formation and Treatment || DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential

Khanna, Kum Kum, Shiloh, Yosef

Year:

2009

Language:

english

File:

PDF, 899 KB

english, 2009

35

Systemic-oral immunization with 56 KDa molecule of Giardia lamblia affords protection in experimental mice

V.K. Vinayak, Kum Kum, Rajiv Khanna

Journal:

Year:

1992

Language:

english

File:

PDF, 105 KB

english, 1992

36

Systemic-oral immunization with 56 kDa molecule of Giardia lamblia affords protection in experimental mice

V.K. Vinayak, Kum Kum Rajiv Khanna, Madhu Khuller

Journal:

Year:

1992

Language:

english

File:

PDF, 952 KB

english, 1992

37

Cloning and characterization of a human protein phosphatase 1-encoding cDNA

Song, Qizhong, Khanna, Kum Kum, Lu, Hong, Lavin, Martin F.

Journal:

Year:

1993

Language:

english

File:

PDF, 648 KB

english, 1993

38

Centrobin regulates centrosome function in interphase cells by limiting pericentriolar matrix recruitment

Jeffery, Jessie M., Grigoriev, Ilya, Poser, Ina, van der Horst, Armando, Hamilton, Nicholas, Waterhouse, Nigel, Bleier, Jonathan, Subramaniam, V. Nathan, Maly, Ivan V., Akhmanova, Anna, Khanna, Kum Ku

Journal:

Year:

2013

Language:

english

File:

PDF, 2.34 MB

english, 2013

39

The DNA Damage Response: Implications on Cancer Formation and Treatment || The Fanconi anemia-BRCA Pathway and Cancer

Khanna, Kum Kum, Shiloh, Yosef

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

40

From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health

Papp, Laura Vanda, Lu, Jun, Holmgren, Arne, Khanna, Kum Kum

Journal:

Antioxidants & Redox Signaling

Year:

2007

Language:

english

File:

PDF, 723 KB

english, 2007

41

Are estrogen receptor-positive breast cancers inBRCA1mutation carriers sporadic?

Sunil R Lakhani, Kum Kum Khanna, Georgia Chenevix-Trench

Journal:

Breast Cancer Research

Year:

2010

Language:

english

File:

PDF, 123 KB

english, 2010

42

Selenoprotein S is a marker but not a regulator of endoplasmic reticulum stress in intestinal epithelial cells

Speckmann, Bodo, Gerloff, Kirsten, Simms, Lisa, Oancea, Iulia, Shi, Wei, McGuckin, Michael A., Radford-Smith, Graham, Khanna, Kum Kum

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 6.60 MB

english, 2014

43

Kinetics of intraepithelium and lamina propria lymphocyte responses during Giardia lamblia infection in mice

Vinayak, V.K., Khanna, R., Kum, Kum

Journal:

Microbial Pathogenesis

Year:

1991

Language:

english

File:

PDF, 442 KB

english, 1991

44

Supplement: Molecular, Cellular, and Genetic Basis of Radiosensitivity at Low Doses: A Case of Induced Repair? || Ionizing Radiation and Cell Cycle Progression in Ataxia Telangiectasia

Heather Beamish, Kum Kum Khanna and Martin F. Lavin

Journal:

Radiation Research

Year:

1994

Language:

english

File:

PDF, 861 KB

english, 1994

45

INTS3 Controls the hSSBl -Mediated DNA Damage Response

Jeffrey R. Skaar, Derek J. Richard, Anita Saraf, Alfredo Toschi, Emma Bolderson, Laurence Florens, Michael P. Washburn, Kum Kum Khanna and Michele Pagano

Journal:

The Journal of Cell Biology

Year:

2009

Language:

english

File:

PDF, 1.72 MB

english, 2009

46

Review: ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia

F. Lavin, Kum Kum Khanna, Martin

Journal:

International Journal of Radiation Biology

Year:

1999

Language:

english

File:

PDF, 324 KB

english, 1999

47

SECIS-Binding Protein 2 Promotes Cell Survival by Protecting Against Oxidative Stress

Papp, Laura V., Lu, Jun, Bolderson, Emma, Boucher, Didier, Singh, Ravindra, Holmgren, Arne, Khanna, Kum Kum

Journal:

Antioxidants & Redox Signaling

Year:

2010

Language:

english

File:

PDF, 14.89 MB

english, 2010

48

The Integrator complex controls the termination of transcription at diverse classes of gene targets

Skaar, Jeffrey R, Ferris, Andrea L, Wu, Xiaolin, Saraf, Anita, Khanna, Kum Kum, Florens, Laurence, Washburn, Michael P, Hughes, Stephen H, Pagano, Michele

Journal:

Year:

2015

Language:

english

File:

PDF, 1.81 MB

english, 2015

49

Tumor protein D52 represents a negative regulator of ATM protein levels

Chen, Yuyan, Kamili, Alvin, Hardy, Jayne, Groblewski, Guy, Khanna, Kum Kum, Byrne, Jennifer

Journal:

Year:

2013

Language:

english

File:

PDF, 4.12 MB

english, 2013

50

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

Kalousi, Alkmini, Hoffbeck, Anne-Sophie, Selemenakis, Platonas N., Pinder, Jordan, Savage, Kienan I., Khanna, Kum Kum, Brino, Laurent, Dellaire, Graham, Gorgoulis, Vassilis G., Soutoglou, Evi

Journal:

Year:

2015

Language:

english

File:

PDF, 5.33 MB

english, 2015